没女朋友的请拿走：

from tkinter import *
from tkinter import messagebox
import random

def no_close():
return

def close_all_window():
window.destroy()

def close_window():
messagebox.showinfo(title="不要嘛~", message="不选好不许走！")

def Love():
love = Toplevel(window)
love.geometry("300x100+580+250")
love.title("爱你么么哒~")
btn = Button(love, text="在一起！", width=10, height=2, command=close_all_window)
btn.place(x=100, y=30)
love.protocol("WM_DELETE_WINDOW", no_close)

window = Tk()
window.title("嗨，小姐姐")
window.geometry("360x640+550+50")
window.protocol("WM_DELETE_WINDOW", close_window)
label = Label(window, text="观察你很久了", font=("微软雅黑", 18))
label.place(x=120, y=50)
label = Label(window, text="做我女朋友好不好？", font=("微软雅黑", 24))
label.place(x=70, y=100)

btn1 = Button(window, text="好", width=15, height=2, command=Love)
btn1.place(x=110, y=200)
pos = [110, 300]
btn2 = Button(window, text="不好", width=15, height=2)
btn2.place(x=pos[0], y=pos[1])
def on_enter(e):
global pos
dx = random.randint(100, 200)
dy = random.randint(100, 300)
print(pos,dx,dy)
pos = (pos[0] + dx) % 200, (pos[1] - 250 + dy) % 350 + 250
btn2.place(x=pos[0], y=pos[1])

btn2.bind("<Enter>", on_enter)
window.mainloop()